About & methods
OrisCura is a chairside reference that connects systemic health and the mouth. Content is curated from the dental and medical literature. It is not AI-generated.
Who makes OrisCura
OrisCura is created and curated by Sophie Knott, RDH, a registered dental hygienist, to put the oral–systemic connection at the chairside in seconds.
Clinical review status
Every entry is sourced from the cited literature. An independent clinical review of the full library is in progress. Until it is complete, treat entries as a starting point and verify against the cited sources and current guidelines. Entries that have been reviewed show a “Last clinically reviewed” date at the bottom of their page.
Spotted an error? Please report it with the suggestion box on any page. Corrections are reviewed and applied promptly.
How AI is used
The clinical content on OrisCura (conditions, medications, oral effects, ratings, and citations) is manually curated from the dental and medical literature. It is not generated, selected, or summarized by AI. AI assistance (Claude Code) was used to help build the application itself: its code, design, and features. That distinction matters: the tool you're using was AI-assisted, but the clinical judgments in it were not.
Two separate ratings
We deliberately keep two ratings apart because they answer different questions. A link can be strong but under-studied, or well-studied but weak.
How strong or prevalent the association is: how likely a condition affects the mouth, or how impactful a perio-systemic link is.
How robust the peer-reviewed evidence is, graded by an evidence hierarchy.
How evidence confidence is graded
- High: supported by systematic reviews, meta-analyses, or consistent RCT / large cohort evidence.
- Moderate: supported by cohort or case-control studies with generally consistent findings.
- Low: based on case reports, mechanistic plausibility, expert opinion, or conflicting data.
We intentionally use a Low/Moderate/High scale rather than precise percentages, which the literature rarely supports honestly.
Medical disclaimer
Clinical decision-support only. For use by licensed dental professionals. Not a substitute for professional judgment or a complete drug reference. Always verify with primary sources. This is not individualized medical advice. Ratings and summaries are simplifications of complex, evolving evidence: check current guidelines too, and consult the patient's physician where appropriate.