Hypothyroidism
Endocrine
Likelihood of oral impactModerate
How likely this condition is to affect the mouth.
Evidence confidenceLow
Strength of the peer-reviewed evidence.
Oral health effects
Enlarged tongue and delayed tooth eruption (macroglossia), mainly congenital
Untreated or congenital hypothyroidism can be associated with an enlarged tongue and delayed tooth eruption; adult effects are subtler.
Clinical management: Ensure medical management; monitor; effects are limited in treated adults.
Worse gum health (periodontitis association)
People with thyroid disease, especially hypothyroidism, show worse periodontal status (deeper pockets, more attachment loss) than healthy controls.
Clinical management: Do a full periodontal charting; treat and maintain periodontitis; ask whether thyroid replacement is stable.
Sources
- A Patient with Hypothyroidism in Need of Periodontal Connective Tissue Graft Surgery. Aldosary SN, Mirfendereski P, Mupparapu M. Dental clinics of North America, 2023.
- [Oral and dental expression of thyroid diseases]. Wémeau JL, Do Cao C, Ladsous M. Presse medicale (Paris, France : 1983), 2017.
- Periodontal disease in patients with thyroid diseases: A systematic review with meta-analysis. Ortarzewska M, Nijakowski K, Jankowski J, et al. Advances in medical sciences, 2024.
- The effects of thyroid function on periodontal status: a systematic review and meta-analysis. Ni J, Dan B, Lei F. BMC oral health, 2025.