Atomoxetine
ADHD agent (norepinephrine reuptake inhibitor)
Brand names: Strattera
Oral health effects
Xerostomia (dry mouth)
Reduced salivary flow raising caries, candidiasis, and mucosal discomfort risk.
Clinical management: Hydration, sugar-free gum/xylitol, salivary substitutes, high-fluoride products; reinforce caries prevention.
Bruxism
Antidepressant-associated jaw clenching/grinding can occur or worsen.
Clinical management: Assess for wear; consider an occlusal guard; discuss with prescriber if severe.
Sources
- A Guide to Medications Inducing Salivary Gland Dysfunction, Xerostomia, and Subjective Sialorrhea: A Systematic Review Sponsored by the World Workshop on Oral Medicine VI. Wolff A, Joshi RK, Ekström J, et al. Drugs in R&D, 2017.
- Adverse drug events in the oral cavity. Yuan A, Woo SB. Oral surgery, oral medicine, oral pathology and oral radiology, 2015.
- Association between psychotropic medications and presence of sleep bruxism: A systematic review. Melo G, Dutra KL, Rodrigues Filho R, et al. Journal of oral rehabilitation, 2018.