Carvedilol
Beta-blocker (non-selective, alpha-blocking)
Brand names: Coreg
Oral health effects
Xerostomia
Dry mouth reported.
Clinical management: Hydration, salivary support, caries prevention.
Dizziness on standing (orthostatic hypotension)
Carvedilol has alpha-blocking as well as beta-blocking activity; postural hypotension occurred in 1.8% of hypertensive patients and hypotension/postural hypotension in 9.7% of heart-failure patients (up to 20% after myocardial infarction).
Clinical management: Raise the chair back slowly at the end of the appointment, let the patient sit upright for 1–2 minutes before standing, and steady them as they get up. Take extra care in older patients, after long supine procedures and when other blood-pressure-lowering drugs are taken.
Sources
- A Guide to Medications Inducing Salivary Gland Dysfunction, Xerostomia, and Subjective Sialorrhea: A Systematic Review Sponsored by the World Workshop on Oral Medicine VI. Wolff A, Joshi RK, Ekström J, et al. Drugs in R&D, 2017.
- Carvedilol prescribing information (FDA label) QPharma Inc / DailyMed, 2026.