Combined oral contraceptive (estrogen/progestin)
Hormonal contraceptive
Brand names: Various
Oral health effects
Exaggerated gingival inflammation
Sex hormones can heighten the gingival inflammatory response to plaque (historically more so with older high-dose formulations).
Mechanism: Hormonal modulation of gingival vasculature and immune response.
Clinical management: Reinforce plaque control; note historical reports of higher dry-socket risk after extraction.
Sources
- Adverse drug events in the oral cavity. Yuan A, Woo SB. Oral surgery, oral medicine, oral pathology and oral radiology, 2015.