Edoxaban
Direct oral anticoagulant (factor Xa inhibitor)
Brand names: Savaysa, Lixiana
Oral health effects
Prolonged / increased bleeding
Increased bleeding tendency during and after invasive dental procedures (extractions, scaling and root planing, surgery). Once-daily DOAC; manage bleeding locally.
Clinical management: Use local hemostatic measures (pressure, sutures, oxidized cellulose, tranexamic acid mouthwash). For most procedures, do not interrupt therapy without physician consultation; plan early-day, atraumatic treatment.
Sources
- Management of dental patients taking anticoagulants or antiplatelet drugs (SDCEP guidance). Scottish Dental Clinical Effectiveness Programme. SDCEP, 2022.