Erythromycin
Antibiotic (macrolide)
Brand names: Ery-Tab
Oral health effects
Antibiotic-associated diarrhea / gut dysbiosis
GI upset is common; alters gut flora.
Clinical management: A probiotic (e.g., Saccharomyces boulardii) during the course may modestly lower the risk of antibiotic-associated diarrhea; the evidence is low certainty. Avoid probiotics in immunocompromised or severely ill patients. See the Gut Health page.
Oral candidiasis (thrush)
Broad-spectrum antibiotics suppress commensal bacteria, allowing Candida overgrowth in the mouth.
Mechanism: Loss of competitive inhibition from normal flora.
Clinical management: Watch for thrush, especially with repeated courses; treat with an antifungal; reinforce hygiene.
Sources
- Adverse drug events in the oral cavity. Yuan A, Woo SB. Oral surgery, oral medicine, oral pathology and oral radiology, 2015.