Clinical decision-support only. For use by licensed dental professionals. Not a substitute for professional judgment or a complete drug reference. Always verify with primary sources.
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Medication

Imatinib

Targeted therapy (BCR-ABL tyrosine kinase inhibitor)

Brand names: Gleevec

Oral health effects

  • Mucosal edema / hypopigmentation / dysgeusia

    Periorbital and oral mucosal edema, mucosal hypopigmentation, and taste changes are reported.

    Clinical management: Reassure and document; symptomatic care.

Sources

  1. A review and guide to drug-associated oral adverse effects-Dental, salivary and neurosensory reactions. Part 1. Teoh L, Moses G, McCullough MJ. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2019.
  2. Adverse drug events in the oral cavity. Yuan A, Woo SB. Oral surgery, oral medicine, oral pathology and oral radiology, 2015.