Clinical decision-support only. For use by licensed dental professionals. Not a substitute for professional judgment or a complete drug reference. Always verify with primary sources.
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Medication

Metoprolol

Beta-blocker (cardioselective)

Brand names: Lopressor, Toprol-XL

Oral health effects

  • Xerostomia

    Dry mouth is reported with beta-blockers.

    Clinical management: Hydration, salivary substitutes, caries prevention.

  • Lichenoid drug reaction

    Beta-blockers can trigger oral lichenoid reactions.

    Clinical management: Identify temporal association; biopsy if diagnosis is unclear; liaise with physician.

Sources

  1. A Guide to Medications Inducing Salivary Gland Dysfunction, Xerostomia, and Subjective Sialorrhea: A Systematic Review Sponsored by the World Workshop on Oral Medicine VI. Wolff A, Joshi RK, Ekström J, et al. Drugs in R&D, 2017.
  2. A review and guide to drug-associated oral adverse effects-Oral mucosal and lichenoid reactions. Part 2. Teoh L, Moses G, McCullough MJ. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2019.