Promethazine

Oral health effects

• Xerostomia

  Anticholinergic dry mouth; sometimes used for nausea or sedation.

  Clinical management: Hydration and caries prevention.

• Involuntary tongue and facial movements (extrapyramidal reactions)

  Extrapyramidal symptoms such as tongue protrusion, torticollis and oculogyric crisis are listed adverse reactions. The label warns that dehydrated, acutely ill children are more susceptible to dystonias. Frequency not stated.

  Clinical management: Recognize sudden tongue protrusion or jaw/neck spasm as a possible drug reaction. Stop the procedure, keep the airway clear and seek medical care. Note it in the history.